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ALL ABOUT DRUGS BY DR ANTHONY MELVIN CRASTO, WORLD DRUG TRACKER, HELPING MILLIONS, MILLION HITS ON GOOGLE, ONE LAKH CONNECTIONS WORLDWIDE.............
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Dr. vinayak pagar( guest blogger) development of a povarov reaction/carbene generation sequence for
Discussing my paper…….. Metal-catalyzed cycloadditions of alkenyldiazo reagents are useful tools to access carbo- and heterocycles. These diazo compounds are chemically sensitive toward both Brønsted orLewis acids. Their reported cycloadditions rely heavily on the formation of metal...
Towards nitrile-substituted cyclopropanes – a slow-release protocol for safe and scalable applicatio
Towards nitrile-substituted cyclopropanes – a slow-release protocol for safe and scalable applications of diazo acetonitrile Green Chem., 2017, Advance Article DOI: 10.1039/C7GC00602K, Communication Katharina J. Hock, Robin Spitzner, Rene M. Koenigs Applications of diazo acetonitrile in...
Dimethylcarbamoyl chloride, a known carcinogen
Identifiers CAS Number 79-44-7 ECHA InfoCard 100.001.099 PubChem 6598 Properties Chemical formula C3H6ClNO Dimethylcarbamoyl Chloride Mechanisms for the Formation of Dimethylcarbamoyl Chloride Thionyl chloride is the most common reagent in process chemistry for the conversion of a carboxylic acid...
Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesic
Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease Med. Chem. Commun., 2017, Advance Article DOI: 10.1039/C6MD00707D, Research Article E. Lattmann, J. Sattayasai, R. Narayanan, N. Ngoc, D. Burrell,...
Award for me, 100 most impactful health care leaders, global listing
At award function for my award “100 Most Impactful Health care Leaders Global listing”, conferred on me at Taj lands end, Mumbai, India on 14 Feb 2014 by World Health Wellness congress and awards...
tert-butyl(3aR,6aS)-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate tert-Butyl (3aR,6aS)-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (1) pure compound 1 (1.051 kg, 67%) as a white solid. Mp: 70–71 °C (uncorrected); [α]25D +0.40° (c 1.00 CHCl3); % purity: 98.5% (HPLC); 1H NMR...
(3R)-4-[2-chloro-6-[[(R)-methylsulfinyl]methyl]pyrimidin-4-yl]-3-methyl-morpholine Synthesis of (3R)-4-[2-chloro-6-[[(R)-methylsulfinyl]methyl]pyrimidin-4-yl]-3-methyl-morpholine (10) off-white solid (53.9 kg, 68.3% yield). 1H NMR (400 MHz, DMSO-d6, δ): 1.20 (d, J = 6.8 Hz, 3 H), 2.52 (m, 1...
(±)-trans-ethyl 2-(3,4-difluorophenyl)Cyclopropanecarboxylate C12H12F2O2 GC-MS (EI) m/z: [M]+ calc. for C12H12F2O2 + : 226.08; found: 226.08. δH (400 MHz, CDCl3): 1.25 (1H, ddd, 3 J 8.4 Hz, 3 J 6.4 Hz, 2 J 4.5 Hz , 3-H); 1.28 (3H, t 3 J 6.4 Hz CH3Ethyl) 1.57-1.62 (2H, m, 3 J 9.2 Hz, 3 J 5.2 Hz,...
tert-Butyl 3a,4,7,7a-Tetrahydro-1H-isoindole-2(3H)-carboxylate tert-Butyl 3a,4,7,7a-Tetrahydro-1H-isoindole-2(3H)-carboxylate as a brown oil. % Purity: 93.72% (GC); 1H NMR (CDCl3, 400 MHz) δ: 1.47 (s, 9H), 1.89–194 (m, 2H), 2.20–2.33 (m, 4H), 3.08 (dd, J1 = 6.2 Hz, J2= 10.2 Hz, 1H), 3.17...
2,2′-(1-(tert-Butoxycarbonyl)pyrrolidine-3,4-diyl)diacetic Acid 2,2′-(1-(tert-Butoxycarbonyl)pyrrolidine-3,4-diyl)diacetic Acid as a white solid. Mp: 162–163 °C, % purity: 94.09% (HPLC); 1H NMR (DMSO-d6, 400 MHz) δ: 1.38 (s, 9H), 2.10–2.18 (m, 2H), 2.28–2.32 (m, 2H), 2.49–2.50 (m, 2H,...
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